Describes the mechanisms of B cell interactions with TFH and FDCs during a germinal centre reaction, and how these interactions regulate the B cell's localisation

Influence of the microbiome of immune development and function Disease association

Importance of innate immunity in defence against viral infections Pattern recognition receptors Cytokines and IFNs Complement NK cells

Innate lymphoid cells: Activation function Similarity to adaptive counterparts Including ILC1,2,3

Stages in lymphocyte development and their function Factors required for developmental progression

Signalling downstream of the TCR and BCR Antigen dependent and independent signalling Associated diseases

Metabolic requirements of activated vs quiescent T cells Coupling of metabolic programs to TCR signalling

Antigen processing for presentation on MHC I Peptide editing and quality control Structure of MHC I Non-classical MHC I and proposed functions

Requirements and function of immunology at mucosal surfaces

How the 3D arrangement of the genome in the nucleus and non-coding transcription facilitate VDJ recombination