Lewis wolpert Study guides, Class notes & Summaries

- Explain the significance of the neural crest lineage to vertebrate anatomy. - Distinguish the ventral-lateral and dorsal pathways of neural crest migration. - Give examples of cell types derived from specific AP regions of neural crest. - Describe and interpret experiments used to ‘fate map’ neural crest cells in avian embryos. - Describe and interpret experiments used to determine the developmental potential of neural crest cells in avian embryos.

-Describe and interpret the embryological experiments that demonstrated a role for the notochord and floorplate in motor neuron induction. -Describe and interpret the experiments that show Shh acts as a morphogen to pattern the ventral neural tube. -Be able to explain the concept of morphogen using examples. -Describe the Shh signal transduction pathway.

- Describe the different types of animal body symmetry and the main body axes of bilaterally symmetrical animals. - Describe the features that define diploblasts versus triploblasts. - Describe the features that define protostomes versus deuterostomes. - Understand the importance of the Ediacaran and Cambrian fauna in animal evolution. - Describe the common features of phylotypic stage chordate embryos. - Discuss the evidence indicating that Pax6 is a conserved regulator of eye development. - ...

- Appreciate and describe the molecular mechanisms underlying neural induction - Describe TGF-beta (TGF-β) signal transduction and the differences between the BMP versus nodal pathways - Discuss the experiments that demonstrate a role for BMP antagonists in vertebrate neural induction - Describe how antisense morpholino oligos can be used to inhibit gene function - Appreciate and describe the differences between the processes of neural induction versus neurogenesis

- Describe the experimental evidence supporting a conserved pathway for regulating neurogenesis in animals - Discuss the conserved function of proneural genes in neurogenesis - Discuss the conserved function of neurogenic genes in neurogenesis - Describe the role of lateral inhibition in selecting neural precursors - Describe the conserved role of notch-delta signalling in mediating lateral inhibition - Appreciate and discuss the distinct processes of neural induction, neurogenesis and neurulati...

Summary molecular principles of development lecture 1-6. You can purchase the bundle 'molecular principles of development' to get the summary of all lectures and an overview of key concepts for the exam.

Summary molecular principles of development lecture 7-11. You can purchase the bundle 'molecular principles of development' to get the summary of all lectures and an overview of key concepts for the exam.

This document can be used as extra study material and consists of all the main topic you should know for the exam. These concepts refer to the summary of molecular principles of development which is also available.

Summary Molecular Principles of Development Includes lectures and a summary of the book Principles of Developmet (Wolpert et al.).

this is a chapter one note of the book the unnatural nature of science and it includes each section of the first chapter into notes please enjoy gives a handful of information that explains the first chapter