DNA Replication and DNA Repair Part 2
Part 2 of DNA Replication and repair, specifically looking at how chromosomes are replicated using accessory proteins and summarising all the proteins forming the machine in DNA replication. Analysing each of these proteins in detail: DNA topoisomerases, telomerase and so on. Briefly looking at the differences between eukaryotes and bacteria in terms of end-replication of chromosomes.
Analysing in detail the process of DNA repair, it's importance and the spontaneous changes that can give rise to DNA mutations/damage. Looking at different pathways by which DNA damage can be removed via base excision repair and nucleotide excision repair, non-homologous end-joining and homologous recombination.
Overview and brief summary included at the end.
These notes are useful in any module covering DNA replication and DNA repair.
[Achieved 1st class in 1st year with these notes.]