Class notes
LIFE305 Cell Signalling in Health and Disease - Redox signalling
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Lecture focussing on reactive oxygen species (ROS) production by NAD(P)H oxidase, xanthine oxidase and mitochondria, the role of antioxidants and antioxidative pathways (bacteria: OxyR, mammals: Keap1/Nrf2), pathways of ROS clearance (superoxide dismutase, catalase, glutathione), the effects of ROS...
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